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They spent 12 years solving a puzzle. COVID-19 Vaccine Research at U of G Awarded Provincial Funding. LA JOLLAScientists have known for a while that SARS-CoV-2s distinctive spike proteins help the virus infect its host by latching on to healthy cells. Severe adverse reactions to the vaccines have been, , a viral immunologist and associate professor at the University of Guelphs Ontario Veterinary College, during an, interview with Canadian radio personality Alex Pierson, on May 27. FauXi's Great Leap Backwards | The Spectator Australia New research: Besides initiating infection, coronavirus spike protein The, , called 2P, as in two proline molecules, is, No Evidence Vaccine-Generated Spike Protein Is Harmful, prepared in response to the attention brought by the interview, Bridle says the Canadian government should be called upon to immediately halt the mass vaccination program of children and adolescents. He says there is no immediate threat of severe COVID-19 in the majority of Canadian children and adolescents, and that more safety and efficacy data is needed for the use of experimental vaccines., the use of the Pfizer/BioNTech COVID-19 vaccine in children 12 to 15, following authorization of the vaccine in youth 16 years old and older in December. chances of spreading. Previous studies have shown a similar effect when cells were exposed to the SARS-CoV-2 virus, but this is the first study to show that the damage occurs when cells are exposed to the spike protein on its own. a cytokine storm. American Cancer Society Professor Tony Hunter previously showed that the cytokine LIF (leukemia I agree that if the mRNA vaccines themselves stimulate the human bodys cells to produce spike proteins, shouldnt there be some concern that by this process the mRNA vaccines could ultimately cause the same vascular damage? Dr. Jeannie Kelly, an assistant professor of obstetrics and gynecology at the Washington University School of Medicine in St. Louis and lead author of a study on SARS-CoV-2 antibodies in breast milk following vaccination, told us there is no evidence to support Bridles claims. test whether cytokines, like LIF, play a role in the immune Your comment is exactly the type of thing that fails the smell test. If a burgler, theoretically, is born inside your house and cannot get out alive and is killed by the residents, there is no damage and no damage in the future at other houses. If you remove the replicating capabilities of the virus, it still has a major damaging effect on the vascular cells, simply by virtue of its ability to bind to this ACE2 receptor, the S protein receptor, now famous thanks to COVID, Manor explains. Other enzymes destroy the spike proteins and parts of it will be presented to the immune system outside the cell. Unless the MRNA vaccine gets into one of your cells exactly while its splitting, past the cell wall, past the cell nucleus, guide its self into the exact spot it can attach its self to your cells own RNA (when dividing) its not going to cause any harm to your body. The cells genetic machinery reads the mRNAs instructions, and any leftover mRNA is ultimately destroyed by the cell. Our conclusion was that the vaccine is working as intended.. New research: Besides initiating infection, coronavirus spike protein has key role in illness The paper also finds that Covid-19 is a vascular disease, demonstrating exactly how the SARS-CoV-2 virus damages and attacks the vascular system (comprising the blood vessels) on a cellular level. 02 The Lyumkis lab will also explore how the nonstructural Antisevere acute respiratory syndrome coronavirus 2 antibodies induced in breast milk after Pfizer-BioNTech/BNT162b2 vaccination. if and how long-term immunity can be established. Other immune cells will be activated that can seek out and destroy future coronavirus-infected cells displaying the spike. See: https://www.regulations.gov/document/FDA-2020-N-1898-0246. My statement that the spike protein migrates to the surface of the cell so as to be recognized by the immune system is not a very accurate simplification. generating protective immunity. Pharmacokinetics is the study of how a drug moves through the body, including how quickly drugs are absorbed, metabolized, and excreted. levels in the lungs alter the course of the disease. 14. University of Guelph. The study, in which researchers administered a pseudovirus to hamsters, found the spike protein alone can damage vascular endothelial cells. But as the authors mention, the use of a pseudovirus is a limitation and findings need to be confirmed with the SARS-CoV-2 virus in the future. However, the websites are also saying all travelers must be fully vaccinated to depart from Frankfurt. Watch this explanation. The premise of this study is the Spike proteins are attaching to the epithelial cells that line our circulatory system. SARS-CoV-2 Spike Protein Impairs Endothelial Function via Further studies with mutant spike proteins will also provide new insight towards the infectivity and severity of mutant SARS CoV-2 viruses.. This is because the normal spike protein must change its shape in order to achieve fusion with the ACE2 receptor. And so theres no risk of transmission through the breast milk. spike protein, SARS-CoV-2 Angiotensin-Converting Enzyme 2 Grant support R01 HL106579/HL/NHLBI NIH HHS/United States . Were on the receiving end of a very incomplete picture from mainstream media because they dont want to encourage vaccine hesitancy. Hall, Shannon. The information is still valuable because its a way of being quickly alerted to a potential safety issue with a vaccine, which can then be followed-up by government scientists. 31 Mar 2021. I imagine the commenter who thought that spike making cells destroyed would release unnattached spike protein into the body was correct. We did not measure spike protein levels in our study. Which is totally different from the wild version. Salk researchers and collaborators show how the protein damages cells, confirming COVID-19 as a primarily vascular disease, Home - 23 June 2021. Salk researchers and collaborators show how the protein damages cells, confirming COVID-19 as a primarily vascular disease. The 15-minute video shows three individuals discussing the COVID-19 vaccine and the spike protein is repeatedly described as "very dangerous" and "cytotoxic.". 367, Issue 648313. And I understand some clots as well, including with the Pfizer vaccine.I am asking this also because I want to get vaccinated but just like the previous comment with the autoimmune condition, I have had an autoimmune condition, the hives on and off for the past 15years (I am not that young anymore though), cause unknown although stress and some chemicals make them worse. Multiple vaccines are now available to help curb the threat of COVID-19, caused by the SARS-CoV-2 virus. Can I reverse it? 21 . The foundation hasno controlover our editorial decisions, and the views expressed in our articles do not necessarily reflect the views of the foundation. See: https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/975909/S1182_SPI-M-O_Summary_of_modelling_of_easing_roadmap_step_2_restrictions.pdf. The Spike (S) protein of the SARS-CoV-2 virus is critical for its ability to attach and fuse into the host cells, leading to infection, and transmission. Previous studies have shown a similar effect when cells were exposed to the SARS-CoV-2 virus, but this is the first study to show that the damage occurs when cells are exposed to the spike protein on its own. It is not secreted and thus does not float through the body, McLellan said. Only small fragments of the ubiquoitim proteosome protein degradation process of the induced spike protein are presented on the surface of the cell by the MHC 1 ANTIGEN presentation system. Furthermore if vaccine induced spike were pathogenic wouldnt we see a lot of illness following vaccination?, Finally, Bridle says there is evidence that the mRNA vaccines get transferred through breast milk, citing apreprint from Singapore that tested milk samples from 10 lactating health care workers after they were immunized with the Pfizer/BioNTech vaccine. Biodistribution and Spike Protein Safety of mRNA Vaccines: An - Medium Vaccines that trigger spike protein production only affect a very limited number of cells, as the genetic material that these vaccines contain does not auto-replicate in the body. The, unpublished study found antibodies in the breast milk from all of the workers andminimal amounts of vaccine mRNA., document, instead saying that detection of the mRNA was downplayed., is designed to detect potential problems thats why its there but it does not show whether the vaccines. According to a statement sent to FactCheck.org by the National Institute of Allergy and Infectious Diseases, the vaccine-generated spike protein is not secreted into circulation in the bloodstream.. Does that mean people who are vaccinated face the same health risks as COVID-19 itself? This process ultimately However, the displayed parts also cause the innate immune system to attack and destroy the cell wall. Pierre Little | May 3, 2021 at 12:13 pm | Reply. If its comforting, a little back-of-the-envelope math shows that people are at least 50,000 times more likely to die from covid than to get a serious complication from the vaccine. Those experiments were a stepping stone towards two of the most important and profitable vaccines in history: the mRNA-based COVID-19 vaccines given to hundreds of millions of people around the. This explains why the vaccine can make you a little bit ill. Viral Posts Misuse VAERS Data to Make False Claims About COVID-19 Vaccines. FactCheck.org. Im a layman but I think I got it.The damage happens when a free spike protein binds to a cell. And look into the heavens and see the sun and all the stars in Heaven. These include events that happen both in the womb as well as after birth. COVID-19 spike protein damages blood vessels The "spike" proteins that the coronavirus uses to help it break into cells inflicts other damage as well, according to a new study that shines a. mimics the ones on the coronavirus. This is because the spike parts are displayed on the cell. Spokesperson, U.S. Food and Drug Administration. There is no screening or vetting of the report and no attempt to determine if the vaccine was responsible for the problem. Because it is stopped once made, because the cell recognizes is as foreign protein and send it off for destruction, and hands its smashed parts from the endoplasmic reticulum (ER) to the MCH mechanism which hands it off to the T-Cell immune system for removal. A new study co-led by Assistant Research Professor Uri Manor and UC San Diego shows that the proteins also play a key role in the disease itself. Watch this https://youtu.be/9EfToFXwx98?t=479, Wrong. COVID-19 Vaccines and Children: A Scientists Guide for Parents. Canadian Covid Care Alliance. This is how they escape without being torn to pieces. This has been shown to happen by researchers or doctors perfforming a D Dimr test on recently vaccinated people. . Updated 29 June 2021. FactCheck.org reached out to Bridle for comment. McLellan, Jason. The development of the COVID-19 mRNA vaccines was possible, in part, because of the groundwork Holleys foundational science provided. Emails are serviced by Constant Contact. The paper, published on April 30, 2021, in Circulation Research, also shows conclusively that COVID-19 is a vascular disease, demonstrating exactly how the SARS-CoV-2 virus damages and attacks the vascular system on a cellular level. Your support will accelerate the pace of breakthroughs in understanding disease and pave the way to new drug therapies. The findings help explain COVID-19s wide variety of seemingly unconnected complications, and could open the door for new research into more effective therapies. It found that spike protein "was detectable in three of 13 participants . See: https://www.jpost.com/health-science/could-an-mrna-vaccine-be-dangerous-in-the-long-term-649253, If these spike proteins are expressed in endothelial cells, which are found in the vascular system, brain and other organs, the protein can presumably damage that tissue in a way that may not be readily apparent. So its like the spike protein is a burglar. The Canadian Paediatric Society recommends offering the vaccine to all children and adolescents 12 years of age and older as soon as vaccine supply permits., In adocument published in June, Bridle says severe SARS-CoV-2 infections can cause damage to the cardiovascular system and neurological problems.. But theres absolutely no harm. The CDC and FDA vaccine safety monitoring systems, which were expanded for the COVID-19 vaccines and also include a new smartphone-based reporting tool called. "Novel coronavirus' spike protein plays additional key role in illness: Researchers show how the protein damages cells, confirming COVID-19 as a primarily vascular disease.". Accessed 29 June 2021. work will be critical to understanding the types of memory IANS. The majority of people wouldnt even know they had covid. The novel coronavirus' spike protein plays additional key role in illness Salk researchers and collaborators show how the protein damages cells, confirming COVID-19 as a primarily vascular disease LA JOLLAScientists have known for a while that SARS-CoV-2's distinctive "spike" proteins help the virus infect its host by latching on to healthy cells. Interview, Dr. Paul Offit, director of the Vaccine Education Center and an . FACT: The COVID-19 vaccine will not affect fertility. Yes, thats why they induce vascular effects in some cases. surfactant in COVID-19 patients. genetics, immunology, plant biology and more. The team will then examine Accessed 29 June 2021. Show replies. Because the vaccine produced spike proteins are locked into this state, they cannot properly bind to the ACE2 receptors in other, healthy cells. In the absence of the protein EPS8, stereocilia are too short to . It must first be understood by all. As mentioned, the spike protein is itself a pathogen. Circulating SARS-CoV-2 Vaccine Antigen Detected in the Plasma of mRNA-1273 Vaccine Recipients. An overview of spike protein antigen COVID-19 vaccine candidates Ogata, Alana, et al.Circulating SARS-CoV-2 Vaccine Antigen Detected in the Plasma of mRNA-1273 Vaccine Recipients. Clinical Infectious Diseases. Spikes and spike protein fragments move to the outside of the cell and protrude from the surface where they will be recognized by the immune system. Germany has lifted all Covid restrictions for entry into the country. Bryam Bridle profile. to generate a virus system that expresses a spike protein that I wonder what this means for spike protein vaccine safety. Incredibly ignorant. And he can transfuse wiping away this virus. Vaccine protects COVID-19 survivors against variants; virus' spike COVID-19 Vaccines While Pregnant or Breastfeeding. 8 June 2021. Editors note:SciChecks COVID-19/Vaccination Projectis made possible by a grant from the Robert Wood Johnson Foundation. Accessed 29 June 2021. You dumb asses also watched too much resident evil and think thats actual science and it shows. In elderly patients who are not already on deaths door, tolerance appears to be quite good (less, even, of flu-like symptoms post vaccination). Also you become able to look down into the middle of the earth. 20 May 2021. The one Dr. Malone particularly pushed is from Salk Institute, where researchers injected SARS-CoV-2 spike proteins into hamsters, which injured the lungs and blood vessels due to angiotensin . Scientists have known for a while that SARS-CoV-2s distinctive spike proteins help the virus infect its host by latching on to healthy cells. T cells that COVID-19 vaccines will need to re-create Claims that Covid vaccine spike proteins are harmful ar If they are so safe, surely companies should have confidence in their products? There is no risk at all because all the vaccines that are being used presently, none of them have the live virus in it. This frees the (likely many) whole and partial spike proteins inside the cell into the blood. . Canadian Covid Care Alliance. Continue with Recommended Cookies, Representative images of vascular endothelial control cells (left) and cells treated with the SARS-CoV-2 Spike protein (right) show that the spike protein causes increased mitochondrial fragmentation in vascular cells. The point of the article is that the spike protein is dangerous, so if the vaccine is producing spike proteins, its quite a leap in logic to say that the vaccine is safe (whatever definition that is today). What the researchers found was a bit of a surprise: the vast majority of antibodiesabout 84 percenttargeted other portions of the spike protein than the RBD. Anyone who says there is no risk with vaccines is a liar, else why would all throughout history there have been huge billion-dollar payouts for vaccine deaths and injuries? This is the issue, why create spikes inside cellular machinery? 'Toxic' spike protein claims misinterpret vaccine study This treatment will prevent the virus As the old saying goes, where there is smoke there is fire. The CDC and FDA vaccine safety monitoring systems, which were expanded for the COVID-19 vaccines and also include a new smartphone-based reporting tool called v-safe, have subsequently identified only a few, very rare adverse events. Scientists have known for a while that SARS-CoV-2s distinctive spike proteins help the virus infect its host by latching on to healthy cells. Email sent to FactCheck.org. This helps to stop the cytokine storm in the beginning and repairs your lungs (if not to damaged). COVID-19 is really a disease of the blood vessels, coauthor Uri Manor of the Salk Institute for Biological Studies in La Jolla, California said in a statement. So by vaccinating people we are inadvertently inoculating them with a toxin.. And what about those many numbers in the total population who contract the virus, recover with seemingly little damage if any to their vascular system? However, there seems to be no way to predict who that would be. Our Immune Systems Blanket the SARS-CoV-2 Spike Protein with Antibodies . Circulation Research. SARS-CoV-2 spike NTD to RBD Protein Vaccine Improves Immunity Against Viral Variants, iScience (2023). The research was supported by the National Institutes of Health, the National Natural Science Foundation of China, the Shaanxi Natural Science Fund, the National Key Research and Development Program, the First Affiliated Hospital of Xian Jiaotong University; and Xian Jiaotong University. 21 May 2021. a test to detect the presence of COVID-19 genomes in human Furthermore, the study concludes that vaccines not only protect people from SARS-CoV-2 infection, but also from damage to the endothelium, a thin membrane that lines the inside of the heart and blood vessels. Spokesperson, Pfizer. What was claimed. Health Canada authorizes use of the Pfizer-BioNTech COVID-19 vaccine in children 12 to 15 years of age. The same harmless mutation, called 2P, as in two proline molecules, is used in the SARS-CoV-2 vaccines. In fact, the antibodies that the mother has can go through the breast milk to the baby and may only serve maybe to protect the baby a little bit. The mRNA vaccines builds the protein within the safe environment of the host cell structure from the inside outspikes are not created outside this environment. COVID-19 vaccines do not contain a live virus, so there isn't a biological path for a vaccinated person to "shed" the SARS-CoV-2 spike protein to those around them. Here's how San Diego scientists are mounting a counterattack against The body then recognises these as foreign and starts to make antibodies. The study concluded lactating individuals should continue breastfeeding after being vaccinated. The miscegenation seems to be the common factor for the number of new variants from South Africa, Brazil, United Kingdom and the United States. Yes. No.I also got a history of rare autoimmune disease involving the blood vessels.The question is, do these spike proteins stay in the cells long enough to produce any damage ? If you would like to change your settings or withdraw consent at any time, the link to do so is in our privacy policy accessible from our home page.. Updated 21 June 2021. Predicting the efficacy of variant-modified COVID-19 vaccine boosters It is incredibly safe., A second study Bridle uses to support his claims is one by Pfizer. A post widely shared on social media claims a viral immunologist said COVID-19 vaccines' spike protein means people are being inoculated "with a toxin." Experts say there is no evidence that the . And white !!!! Since many cardiovascular diseases are silent killers, those people may have their vascular system very damaged and only show any health problem in the future. Now, a . I just listened to a simplified lecture on why the spike proteins are mostly destroyed inside the cell as some of the pro-vacciners stated. via rigorous testing in clinical trials prior to authorization or approval, followed by continued safety monitoring once the vaccine is rolled out to the public to detect potential rare side effects.